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Schwartz Hunts for Predictive Biomarkers in Soft Tissue Sarcoma Gary K. Schwartz, MD, highlights research that is being done with regard to genomic signatures in sarcoma, challenges faced with immunotherapy, and where the field is headed. Gary K. Schwartz, MD Although several research efforts have been dedicated to evaluating the use of immunotherapy in patients [...]
Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy Efficiency Abstract One of the crucial challenges in the clinical management of cancer is resistance to chemotherapeutics. Multidrug resistance (MDR) has been intensively studied, and one of the most prominent mechanisms underlying MDR is overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) transporters. Despite research efforts to develop compounds [...]
Results of a Prospective Phase 2 Study of Pazopanib in Patients With Surgically Unresectable or Metastatic Chondrosarcoma Warren Chow, MD1; Paul Frankel, PhD2; Chris Ruel, PhD2; Dejka M. Araujo, MD3; Mohammed Milhem, MBBS4; Scott Okuno, MD5; Lee Hartner, MD6; Samir Undevia, MD7; and Arthur Staddon, MD6 BACKGROUND: This single-arm, multicenter, phase 2 study evaluated the [...]
A new article Treating Chondrosarcoma with Urgency and Compassion has just been posted on the Chondrosarcoma Web Site (www.csfshayna.org). You can find the article on the Commentaries page (www.csfshayna.org/commentaries-chondrosarcoma-foundation/). The article examines problems and challenges in treating Chondrosarcoma. The intent of the paper is to give some direction to patients and families who have been [...]
Jeffrey T. Kramer,President: Chondrosarcoma CS Foundation, Inc. Introduction Cancer patients and their families perceive physicians and oncologists as experts in the treatment of cancer. We rely on them for the answers we seek and to prescribe the care that gives the greatest chance to beat cancer. With Chondrosarcoma that is not always the case. Chondrosarcoma [...]
Please check out our Web Site www.csfshayna.org to get acquainted with our board of directors and staff for the Chondrosarcoma Foundation.
Immunotherapy: A New (and Old) Approach to Treatment of Soft Tissue and Bone Sarcomas MICHAEL J. NATHENSON, ANTHONY P. CONLEY, b EDWARD SAUSVILLE, Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; Department of Sarcoma Medical Oncology, MD Anderson Cancer Center, Houston, Texas, USA; Department of Medicine, Greenebaum Cancer Center, and University [...]
To honor the memory of those who came before us and on whose shoulders we stand. Beloved brother of Angela Saunders Storey, 2 Sep 76 – 19 Jul 20 Sébastien Desjardins, 14 Jul 2020, treasured brother of Stéphanie Shayna Elise Kramer, beloved daughter of Lois and Jeffrey, 14 Nov 2019 Stephen Roberts (3 Nov 1960 [...]
EPIGENOMICSVOL. 8, NO. 11SPECIAL REPORT Aberrant DNA methylations in chondrosarcoma Pei Liu , Jacson K Shen , Jianzhong Xu , Carol A Trahan , Francis J Hornicek & Zhenfeng Duan Published Online:30 Sep 2016https://doi.org/10.2217/epi-2016-0071 View Article Tools Share Abstract Chondrosarcoma (CS) is the second most common primary malignant bone tumor. Unlike other bone tumors, CS [...]
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