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    Author Archives for admin

    Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes

    April 24, 2024 3:36 am Published by Comments Off on Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes

    Ryan A Denu 1, Richard K Yang 2, Alexander J Lazar 2 3, Shalin S Patel 4, Valerae O Lewis 4, Jason Roszik 5, J Andrew Livingston 1, Wei-Lien Wang 2, Kenna R Shaw 6, Ravin Ratan 1, Maria A Zarzour 1, Justin Bird 4, Shaan Raza 7, Kadir C Akdemir 7, Jordi Rodon Ahnert [...]


    Chondrosarcoma Foundation Efforts to Promote Genomic Sequencing Tests

    April 22, 2024 4:27 pm Published by Comments Off on Chondrosarcoma Foundation Efforts to Promote Genomic Sequencing Tests

    Genomic sequencing is a promising tool for expanding the treatment options for chondrosarcoma patients. Genomic sequencing technologies are capable of characterizing known and novel clinically relevant biomarkers, like IDH1/2, and is becoming a useful tool for drug development, facilitating drug target discovery, clinical trial patient selection, and clinical correlate analyses to improve the quality and [...]


    Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options

    April 4, 2024 12:36 pm Published by Comments Off on Biology and Management of High-Grade Chondrosarcoma: An Update on Targets and Treatment Options

    Abstract This review provides an overview of histopathology, clinical presentation, molecular pathways, and potential new systemic treatments of high-grade chondrosarcomas (CS), including grade 2–3 conventional, dedifferentiated, and mesenchymal CS. The diagnosis of CS combines radiological and histological data in conjunction with patient clinical presentations. Conventional CS is the most frequent subtype of CS (85%) and [...]


    Metastatic mesenchymal chondrosarcoma showing a sustained response to cabozantinib: A case report

    March 26, 2024 5:39 pm Published by Comments Off on Metastatic mesenchymal chondrosarcoma showing a sustained response to cabozantinib: A case report

    Metastatic mesenchymal chondrosarcoma showing a sustained response to cabozantinib: A case report Veronika Blum, 1 , † Vanghelita Andrei, 2 , † Baptiste Ameline, 2 Silvia Hofer, 3 Bruno Fuchs, 1 Klaus Strobel, 1 Anna Allemann, 1 Beata Bode, 4 and Daniel Baumhoer 2 , * Author information Article notes Copyright and License information PMC [...]


    Chondrosarcoma Foundation Introduces a new Patient Guide: Making the Decision to enroll in a Clinical Trial.

    March 3, 2024 7:46 pm Published by Comments Off on Chondrosarcoma Foundation Introduces a new Patient Guide: Making the Decision to enroll in a Clinical Trial.

    Typically after surgery, it is important to know what post-surgical options are available. Making the decision to enroll in a clinical trial is one of those options and maybe one of the most important decisions chondrosarcoma patients and their families will have to make. It is important to know what a clinical trial offers, what [...]


    Chondrosarcoma Foundation Efforts to Promote Genomic Sequencing

    February 25, 2024 9:23 pm Published by Comments Off on Chondrosarcoma Foundation Efforts to Promote Genomic Sequencing

    Genomic sequencing is a promising tool for expanding the treatment options for chondrosarcoma patients. Genomic sequencing technologies are capable of characterizing known and novel clinically relevant biomarkers, like IDH1/2, and is becoming a useful tool for drug development, facilitating drug target discovery, clinical trial patient selection, and clinical correlate analyses to improve the quality and [...]


    Dan Hurley, M.D. Endowment Fund for Insurance Authorizations

    February 23, 2024 5:38 pm Published by Comments Off on Dan Hurley, M.D. Endowment Fund for Insurance Authorizations

    Daniel Brian Hurley, M.D. passed away August 3, 2023, from dedifferentiated chondrosarcoma at age 50 surrounded by his loved ones. His wife Traci and their three kids Rachel, Sam, and Sarah were the light of his life. His family, including his parents, in-laws, and siblings were very dear to him. In addition to being a [...]


    Call for Action

    February 19, 2024 6:58 pm Published by Comments Off on Call for Action

    Be Part of the First full Analysis of the Chondrosarcoma Patient Registry https://chondrosarcoma.iamrare.org It is not too late to sign up to participate in the Chondrosarcoma Patient Registry. The Chondrosarcoma Foundation has been preparing to conduct the first full statistical analysis of the Chondrosarcoma Patient Registry. The analysis will focus on detailed patient profiling. In [...]


    Thank You for Supporting Chondrosarcoma Awareness Day

    February 8, 2024 5:31 pm Published by Comments Off on Thank You for Supporting Chondrosarcoma Awareness Day

    Thank You!!!! To Everyone that participated in Chondrosarcoma Awareness Day. It is wonderful to see people from all over the globe come together to honor our CS survivors and those who lost their battle to this terrible bone cancer. And it is great to dedicate one day out of the year to shine the spotlight [...]


    Final Tribute and Introduction of the Daniel B. Hurley, M.D. Endowment Fund

    February 5, 2024 6:05 pm Published by Comments Off on Final Tribute and Introduction of the Daniel B. Hurley, M.D. Endowment Fund

    Tomorrow, February 6 is Chondrsarcoma Awareness Day. Join the Fight Wear something Yellow. Take a picture (family, friends, work colleagues) and post it to #cswecare #chondrosarcoma #chondrosarcomafoundation Sign our Petition to support more Research and Clinical Trials: https://csfshayna.org/our-petition/ Daniel Brian Hurley, M.D. passed away August 3, 2023, from dedifferentiated chondrosarcoma at age 50 surrounded by [...]